Comparison of RankGene Measures for ALL-AML Data of Golub et al.

  1. Comparison of measures in terms of the lists of computed genes.
  2. Comparison of measures in terms of the ranks of computed genes.
Comparison of different measures used by RankGene.

Each column shows the best 100 genes selected by the corresponding measure. Using the t-test measure as the gold standard, a gene is highlighted in blue if t-test did not select it among the top 100 genes. A gene selected by the t-test is highlighted in green if it is not selected by at least 2 other measures. The abbreviations for these measures follow the gene name.

t-test (TT)Information gain (IG)Sum of variances (SV)Twoing rule (TR)Gini index (GI)Sum minority (SM)Max minority (MM)1D SVM (1S)
1PROTEASOME IOTA CHAINGlutathione S-transferaseCD33 antigenCD33 antigenCD33 antigenCD33 antigenCD33 antigenDF D component of complement (adipsin)
2CCND3 Cyclin D3CD33 antigenZyxinZyxinZyxinCST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)Zyxin
3TCF3 (E2A immunoglobulin enhancer)ZyxinCST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)ZyxinGlutathione S-transferaseCD33 antigen
4MB-1 geneCST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)Glutathione S-transferaseGlutathione S-transferaseGlutathione S-transferaseCYSTATIN AZyxinCST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)
5ZyxinAmyloid beta precursor-like proteinTCF3 (E2A immunoglobulin enhancer)TCF3 (E2A immunoglobulin enhancer)TCF3 (E2A immunoglobulin enhancer)DF D component of complement (adipsin)TCF3 (E2A immunoglobulin enhancer)TCF3 (E2A immunoglobulin enhancer)
6CD19 gene
( SM MM )
CYSTATIN ACYSTATIN ACYSTATIN ACYSTATIN AGlutathione S-transferaseCYSTATIN ACYSTATIN A
7Terminal transferase mRNADF D component of complement (adipsin)DF D component of complement (adipsin)DF D component of complement (adipsin)DF D component of complement (adipsin)TCF3 (E2A immunoglobulin enhancer)DF D component of complement (adipsin)Glutathione S-transferase
8MYL1 Myosin light chain (alkali)TCF3 (E2A immunoglobulin enhancer)Amyloid beta precursor-like proteinAmyloid beta precursor-like proteinAmyloid beta precursor-like proteinTerminal transferase mRNAAmyloid beta precursor-like proteinTerminal transferase mRNA
9Proteoglycan 1Terminal transferase mRNATerminal transferase mRNATerminal transferase mRNATerminal transferase mRNAAmyloid beta precursor-like proteinSPTAN1CCND3 Cyclin D3
10SPTAN1PFC Properdin P factor, complementPFC Properdin P factor, complementPFC Properdin P factor, complementPFC Properdin P factor, complementPFC Properdin P factor, complementTerminal transferase mRNAAmyloid beta precursor-like protein
11Immunoglobulin-associated beta (B29)CCND3 Cyclin D3CCND3 Cyclin D3CCND3 Cyclin D3CCND3 Cyclin D3CCND3 Cyclin D3CCND3 Cyclin D3CTSD Cathepsin D (lysosomal aspartyl protease)
12HKR-T1ARHG Ras homolog gene family, member G (rho G)GRN GranulinGRN GranulinGRN GranulinGRN GranulinPFC Properdin P factor, complementAzurocidin gene
13GB DEFME491 gene extracted from H.sapiens gene for Me491/CD63 antigenME491 gene extracted from H.sapiens gene for Me491/CD63 antigenME491 gene extracted from H.sapiens gene for Me491/CD63 antigenME491 gene extracted from H.sapiens gene for Me491/CD63 antigenSPTAN1MacmarcksME491 gene extracted from H.sapiens gene for Me491/CD63 antigen
14hSNF2
( SM MM )
GRN GranulinSPTAN1SPTAN1SPTAN1Azurocidin geneNuclear Factor Nf-Il6GRN Granulin
15RABAPTIN-5 protein
( TR SM MM GI SV )
GB DEFAzurocidin geneAzurocidin geneAzurocidin geneME491 gene extracted from H.sapiens gene for Me491/CD63 antigenYamaguchi sarcoma viral related oncogene homologMPO Myeloperoxidase
16Glutathione S-transferasePROTEASOME IOTA CHAINPROTEASOME IOTA CHAINPROTEASOME IOTA CHAINPROTEASOME IOTA CHAINFAH FumarylacetoacetateProtective protein for beta-galactosidaseSPTAN1
17CD19 antigen
( TR SM MM GI SV 1S )
SPTAN1ARHG Ras homolog gene family, member G (rho G)ARHG Ras homolog gene family, member G (rho G)ARHG Ras homolog gene family, member G (rho G)CTSD Cathepsin D (lysosomal aspartyl protease)Oncoprotein 18 (Op18) geneProteoglycan 1
18C-mybMB-1 geneMYL1 Myosin light chain (alkali)MYL1 Myosin light chain (alkali)MYL1 Myosin light chain (alkali)SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1FAH FumarylacetoacetateYamaguchi sarcoma viral related oncogene homolog
19MacmarcksAzurocidin geneCTSD Cathepsin D (lysosomal aspartyl protease)CTSD Cathepsin D (lysosomal aspartyl protease)CTSD Cathepsin D (lysosomal aspartyl protease)PROTEASOME IOTA CHAINCTSD Cathepsin D (lysosomal aspartyl protease)PFC Properdin P factor, complement
20LPAP geneImmunoglobulin-associated beta (B29)FAH FumarylacetoacetateFAH FumarylacetoacetateFAH FumarylacetoacetateMYL1 Myosin light chain (alkali)CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)Protective protein for beta-galactosidase
21Topoisomerase II betaMYL1 Myosin light chain (alkali)SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1MacmarcksAzurocidin geneMB-1 gene
22Oncoprotein 18 (Op18) geneProteoglycan 1GB DEFGB DEFGB DEFNuclear Factor Nf-Il6SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1FAH Fumarylacetoacetate
2326-kDa cell surface protein TAPA-1 mRNA
( IG TR SM MM GI SV )
Recombination activating protein (RAG-1) geneProteoglycan 1Proteoglycan 1Proteoglycan 1Yamaguchi sarcoma viral related oncogene homologGRN GranulinRNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)
24FAH FumarylacetoacetateMPO MyeloperoxidaseMPO MyeloperoxidaseMPO MyeloperoxidaseMPO MyeloperoxidaseMPO MyeloperoxidaseME491 gene extracted from H.sapiens gene for Me491/CD63 antigenMYL1 Myosin light chain (alkali)
25LMP2 genLeukotriene C4 synthase (LTC4S) geneLeukotriene C4 synthase (LTC4S) geneLeukotriene C4 synthase (LTC4S) geneLeukotriene C4 synthase (LTC4S) geneProtective protein for beta-galactosidaseUridine phosphorylaseLeukotriene C4 synthase (LTC4S) gene
26ADP-ribosyltransferase
( SM MM 1S )
CTSD Cathepsin D (lysosomal aspartyl protease)MB-1 geneMB-1 geneMB-1 geneOncoprotein 18 (Op18) geneC-mybPROTEASOME IOTA CHAIN
27Amyloid beta precursor-like proteinFAH FumarylacetoacetateYamaguchi sarcoma viral related oncogene homologYamaguchi sarcoma viral related oncogene homologYamaguchi sarcoma viral related oncogene homologCLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)TIMP2 Tissue inhibitor of metalloproteinase 2Macmarcks
28ATP6C Vacuolar H+ ATPase proton channel subunitSPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)Leukotriene C4 synthase (LTC4S) geneMYL1 Myosin light chain (alkali)CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)
29CD33 antigenCLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)MacmarcksMacmarcksMacmarcksProteoglycan 1KIAA0022 geneTopoisomerase II beta
30OBF-1 mRNA for octamer binding factor 1T cell leukemia geneProtective protein for beta-galactosidaseProtective protein for beta-galactosidaseProtective protein for beta-galactosidaseARHG Ras homolog gene family, member G (rho G)LAMP2 Lysosome-associated membrane protein 2 {alternative products}ARHG Ras homolog gene family, member G (rho G)
31mRNA for calcium channel beta3 subunit
( IG TR SM MM GI SV )
TCRA T cell receptor alpha-chainOncoprotein 18 (Op18) geneOncoprotein 18 (Op18) geneOncoprotein 18 (Op18) geneTopoisomerase II betaMPO MyeloperoxidaseINTERLEUKIN-8 PRECURSOR
32Transcriptional activator hSNF2b
( TR SM GI SV 1S )
Yamaguchi sarcoma viral related oncogene homologNF-IL6-beta protein mRNANF-IL6-beta protein mRNANF-IL6-beta protein mRNANF-IL6-beta protein mRNALEUKOCYTE ELASTASE INHIBITORSPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1
33ALDR1 Aldehyde reductase 1
( IG TR SM GI SV )
OBF-1 mRNA for octamer binding factor 1Nuclear Factor Nf-Il6Nuclear Factor Nf-Il6Nuclear Factor Nf-Il6KIAA0022 genePre-B cell enhancing factor (PBEF) mRNAATP6C Vacuolar H+ ATPase proton channel subunit
34Inducible protein mRNATopoisomerase II betaTopoisomerase II betaTopoisomerase II betaTopoisomerase II betaGB DEFMB-1 geneGB DEF
35TCF3 (E2A immunoglobulin enhancer)
( IG TR SM GI SV )
KIAA0159 geneKIAA0022 geneKIAA0022 geneKIAA0022 geneFTL Ferritin, light polypeptideProteoglycan 1Lysozyme gene (EC 3.2.1.17)
36Nucleoside-diphosphate kinaseBLK Protein-tyrosine kinase blkImmunoglobulin-associated beta (B29)Immunoglobulin-associated beta (B29)Immunoglobulin-associated beta (B29)PYGL Glycogen phosphorylase L (liver form)PROTEASOME IOTA CHAINFTL Ferritin, light polypeptide
37Probable GPCR LCR1 Homolog
( IG 1S )
Protective protein for beta-galactosidaseLEUKOCYTE ELASTASE INHIBITORLEUKOCYTE ELASTASE INHIBITORLEUKOCYTE ELASTASE INHIBITORFc-epsilon-receptor gamma-chain mRNACHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7Inducible protein mRNA
38Yamaguchi sarcoma viral related oncogene homologMacmarcksUridine phosphorylaseUridine phosphorylaseUridine phosphorylaseATP6C Vacuolar H+ ATPase proton channel subunitGLRX Glutaredoxin (thioltransferase)CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7
39Protective protein for beta-galactosidaseOncoprotein 18 (Op18) geneEpb72 gene exon 1Epb72 gene exon 1Epb72 gene exon 1LEUKOCYTE ELASTASE INHIBITORGB DEF = Myosin-IESELL Leukocyte adhesion protein beta subunit
40VIL2 Villin 2 (ezrin)
( IG TR SM GI SV )
KIAA0022 geneRNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)BB1Nucleoside-diphosphate kinasePLECKSTRIN
41DF D component of complement (adipsin)Inducible protein mRNAInducible protein mRNAInducible protein mRNAInducible protein mRNAMB-1 geneOBF-1 mRNA for octamer binding factor 1Interleukin 8 (IL8) gene
42T cell leukemia gene
( SM MM 1S )
PLECKSTRINPLECKSTRINPLECKSTRINPLECKSTRINCHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta
43ARHG Ras homolog gene family, member G (rho G)NF-IL6-beta protein mRNAC-mybC-mybC-mybUridine phosphorylaseTopoisomerase II betaTIMP2 Tissue inhibitor of metalloproteinase 2
44FTL Ferritin, light polypeptideNuclear Factor Nf-Il6TIMP2 Tissue inhibitor of metalloproteinase 2TIMP2 Tissue inhibitor of metalloproteinase 2TIMP2 Tissue inhibitor of metalloproteinase 2C-mybProbable GPCR LCR1 HomologFc-epsilon-receptor gamma-chain mRNA
45IL7R Interleukin 7 receptorIL7R Interleukin 7 receptorFTL Ferritin, light polypeptideFTL Ferritin, light polypeptideFTL Ferritin, light polypeptideMANB Mannosidase alpha-B (lysosomal)SELL Leukocyte adhesion protein beta subunitLYZ Lysozyme
46Clone 22 mRNA, alternative splice variant alpha-1
( IG TR SM MM GI SV 1S )
ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainPYGL Glycogen phosphorylase L (liver form)PYGL Glycogen phosphorylase L (liver form)PYGL Glycogen phosphorylase L (liver form)TIMP2 Tissue inhibitor of metalloproteinase 2NF-IL6-beta protein mRNAhSNF2
47KAI1 Kangai 1
( IG TR SM MM GI SV 1S )
CD19 geneATP6C Vacuolar H+ ATPase proton channel subunitATP6C Vacuolar H+ ATPase proton channel subunitATP6C Vacuolar H+ ATPase proton channel subunitSELL Leukocyte adhesion protein beta subunitEpb72 gene exon 1C-myb
48Liver mRNA for interferon-gamma inducing factor
( IG TR GI SV )
LEUKOCYTE ELASTASE INHIBITORMANB Mannosidase alpha-B (lysosomal)MANB Mannosidase alpha-B (lysosomal)MANB Mannosidase alpha-B (lysosomal)MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonRNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)LYZ Lysozyme
49CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)Uridine phosphorylaseSELL Leukocyte adhesion protein beta subunitSELL Leukocyte adhesion protein beta subunitSELL Leukocyte adhesion protein beta subunitInterferon-gamma induced protein (IFI 16) geneLiver mRNA for interferon-gamma inducing factorNuclear Factor Nf-Il6
50BLK Protein-tyrosine kinase blk
( SM MM 1S )
Epb72 gene exon 1MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonMPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonMPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonEpb72 gene exon 1CalcyclinITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
51CTSD Cathepsin D (lysosomal aspartyl protease)RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)Lysozyme gene (EC 3.2.1.17)Lysozyme gene (EC 3.2.1.17)Lysozyme gene (EC 3.2.1.17)Lysozyme gene (EC 3.2.1.17)TALDO TransaldolaseNF-IL6-beta protein mRNA
52ERC-55 mRNA
( IG TR SM MM GI SV 1S )
PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOROBF-1 mRNA for octamer binding factor 1OBF-1 mRNA for octamer binding factor 1OBF-1 mRNA for octamer binding factor 1RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)ALCAM Activated leucocyte cell adhesion moleculeUridine phosphorylase
53TIMP2 Tissue inhibitor of metalloproteinase 2FTL Ferritin, light polypeptideRecombination activating protein (RAG-1) geneRecombination activating protein (RAG-1) geneRecombination activating protein (RAG-1) geneCATHEPSIN G PRECURSORPCBD 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)LMNA Lamin A
54GB DEF = Topoisomerase type II (Topo II) mRNA, partial cds
( IG TR SM MM GI SV 1S )
PTX3 Pentaxin-related gene, rapidly induced by IL-1 betaCHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7LAMP2 Lysosome-associated membrane protein 2 {alternative products}Inducible protein mRNACD19 gene
55INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECURSOR
( TR SM MM GI SV 1S )
PYGL Glycogen phosphorylase L (liver form)Interferon-gamma induced protein (IFI 16) geneInterferon-gamma induced protein (IFI 16) geneInterferon-gamma induced protein (IFI 16) genePERIPHERAL-TYPE BENZODIAZEPINE RECEPTORFTL Ferritin, light polypeptideLPAP gene
56ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
( SM 1S )
ATP6C Vacuolar H+ ATPase proton channel subunitFc-epsilon-receptor gamma-chain mRNAFc-epsilon-receptor gamma-chain mRNAFc-epsilon-receptor gamma-chain mRNAQuiescin (Q6) mRNA, partial cdsADA Adenosine deaminaseLiver mRNA for interferon-gamma inducing factor
57KIAA0212 gene
( IG TR SM MM GI SV 1S )
MANB Mannosidase alpha-B (lysosomal)BB1BB1BB1Inducible protein mRNAPYGL Glycogen phosphorylase L (liver form)PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR
58Leukotriene C4 synthase (LTC4S) geneSELL Leukocyte adhesion protein beta subunitGB DEF = Myosin-IEGB DEF = Myosin-IEGB DEF = Myosin-IEADA Adenosine deaminaseRecombination activating protein (RAG-1) geneMPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon
59CRYZ Crystallin zeta (quinone reductase)
( IG TR SM MM GI SV 1S )
MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonPERIPHERAL-TYPE BENZODIAZEPINE RECEPTORPERIPHERAL-TYPE BENZODIAZEPINE RECEPTORPERIPHERAL-TYPE BENZODIAZEPINE RECEPTORIL7R Interleukin 7 receptorIL7R Interleukin 7 receptorOncoprotein 18 (Op18) gene
60KIAA0159 gene
( SM MM 1S )
Lysozyme gene (EC 3.2.1.17)PTX3 Pentaxin-related gene, rapidly induced by IL-1 betaPTX3 Pentaxin-related gene, rapidly induced by IL-1 betaPTX3 Pentaxin-related gene, rapidly induced by IL-1 betaPTX3 Pentaxin-related gene, rapidly induced by IL-1 betaPTX3 Pentaxin-related gene, rapidly induced by IL-1 betaL-kynurenine hydrolase mRNA
61ID3 Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
( IG TR SM MM GI SV 1S )
C-mybT cell leukemia geneT cell leukemia geneT cell leukemia genePre-B cell enhancing factor (PBEF) mRNAFc-epsilon-receptor gamma-chain mRNAPre-B cell enhancing factor (PBEF) mRNA
62Translation initiation factor 3 47 kDa subunit mRNA
( IG TR SM MM GI SV 1S )
TIMP2 Tissue inhibitor of metalloproteinase 2TCRA T cell receptor alpha-chainTCRA T cell receptor alpha-chainTCRA T cell receptor alpha-chain(AF1q) mRNAPPBP Connective tissue activation peptide IIILEUKOCYTE ELASTASE INHIBITOR
63LAMP2 Lysosome-associated membrane protein 2 {alternative products}ADP-ribosyltransferaseNucleoside-diphosphate kinaseNucleoside-diphosphate kinaseNucleoside-diphosphate kinaseAcid ceramidase mRNAATP6C Vacuolar H+ ATPase proton channel subunitOBF-1 mRNA for octamer binding factor 1
64RETINOBLASTOMA BINDING PROTEIN P48
( IG TR GI SV 1S )
hSNF2P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)PLECKSTRINACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainHKR-T1
65Calcineurin A catalytic subunit [human, testis, mRNA, 2134 nt]
( IG TR SM MM GI SV 1S )
CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7Nek3 mRNA for protein kinaseLPAP geneNek3 mRNA for protein kinaseGLRX Glutaredoxin (thioltransferase)SPTBN1 Spectrin, beta, non-erythrocytic 1LRPAP1 Low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1
66MCM3 Minichromosome maintenance deficient (S. cerevisiae) 3
( IG TR SM GI SV 1S )
Interferon-gamma induced protein (IFI 16) geneLPAP geneNek3 mRNA for protein kinaseLPAP geneGB DEF = Myosin-IEHKR-T1PRKCD Protein kinase C, delta
67PAGA Proliferation-associated gene A (natural killer-enhancing factor A)
( SM MM 1S )
Fc-epsilon-receptor gamma-chain mRNACalcyclinCalcyclinCalcyclinNucleoside-diphosphate kinaseBB1IL7R Interleukin 7 receptor
68Thymopoietin (TMPO) gene
( IG TR SM MM GI SV 1S )
BB1LAMP2 Lysosome-associated membrane protein 2 {alternative products}LAMP2 Lysosome-associated membrane protein 2 {alternative products}LAMP2 Lysosome-associated membrane protein 2 {alternative products}Nek3 mRNA for protein kinase(AF1q) mRNAKIAA0022 gene
69IGHM Immunoglobulin mu
( IG TR SM GI SV 1S )
GB DEF = Myosin-IEPre-B cell enhancing factor (PBEF) mRNAPre-B cell enhancing factor (PBEF) mRNAPre-B cell enhancing factor (PBEF) mRNAOBF-1 mRNA for octamer binding factor 1Spermidine/spermine N1-acetyltransferase (SSAT) gene26-kDa cell surface protein TAPA-1 mRNA
70GB DEF = Retinoblastoma susceptibility protein (RB1) gene, with a 3 bp deletion in exon 22 (L11910 bases 161855-162161)
( IG TR SM MM GI SV 1S )
NPY Neuropeptide YGLRX Glutaredoxin (thioltransferase)GLRX Glutaredoxin (thioltransferase)GLRX Glutaredoxin (thioltransferase)P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)HOXA9 Homeo box A9CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)
71Interferon-gamma induced protein (IFI 16) geneRABAPTIN-5 proteinQuiescin (Q6) mRNA, partial cdsQuiescin (Q6) mRNA, partial cdsQuiescin (Q6) mRNA, partial cdsMACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORLeukotriene C4 synthase (LTC4S) geneLAMP2 Lysosome-associated membrane protein 2 {alternative products}
72PCBD 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
( IG TR SM GI SV 1S )
CD19 antigenADA Adenosine deaminaseADA Adenosine deaminaseADA Adenosine deaminaseKIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologSmall GTP-binding protein mRNAAcid ceramidase mRNA
73Thymopoietin beta mRNA
( IG TR SM MM GI SV 1S )
Calcyclin(AF1q) mRNA(AF1q) mRNA(AF1q) mRNAITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)L-kynurenine hydrolase mRNAALDR1 Aldehyde reductase 1
74RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)PAGA Proliferation-associated gene A (natural killer-enhancing factor A)KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologKIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologKIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologCD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)Acid ceramidase mRNAGRO2 GRO2 oncogene
7514-3-3 PROTEIN TAU
( IG TR SM MM GI SV 1S )
LPAP geneITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)LPAP geneLOT1 mRNALYZ Lysozyme
76KIAA0084 gene, partial cds
( IG TR SM MM GI SV 1S )
B94 PROTEINAcid ceramidase mRNAAcid ceramidase mRNAAcid ceramidase mRNAHunc18b2DNA binding protein homolog (DRIL) mRNA, partial cdsBB1
77RPA1 Replication protein A1 (70kD)
( IG TR SM MM GI SV 1S )
LYZ LysozymeCATHEPSIN G PRECURSORCATHEPSIN G PRECURSORCATHEPSIN G PRECURSORPRKCD Protein kinase C, deltaDihydropyrimidinase related protein-2PI Protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin
78TCF12 Transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)
( IG TR SM MM GI SV 1S )
Nucleoside-diphosphate kinaseIL7R Interleukin 7 receptorIL7R Interleukin 7 receptorIL7R Interleukin 7 receptorLiver mRNA for interferon-gamma inducing factorPLECKSTRINMANB Mannosidase alpha-B (lysosomal)
79MSH2 DNA repair protein MSH2
( IG TR SM MM GI SV 1S )
P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORMACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORMACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORCalcyclinALDR1 Aldehyde reductase 1Phosphotyrosine independent ligand p62 for the Lck SH2 domain mRNA
80Putative enterocyte differentiation promoting factor mRNA, partial cds
( IG TR SM MM GI SV 1S )
Nek3 mRNA for protein kinaseCD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)Recombination activating protein (RAG-1) geneGRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR(AF1q) mRNA
81HMG1 High-mobility group (nonhistone chromosomal) protein 1
( IG TR SM MM GI SV 1S )
INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECURSORhSNF2hSNF2hSNF2PPBP Connective tissue activation peptide IIIVIL2 Villin 2 (ezrin)Immunoglobulin-associated beta (B29)
82TCRA T cell receptor alpha-chain
( SM MM 1S )
HKR-T1KIAA0159 geneKIAA0159 geneKIAA0159 geneImmunoglobulin-associated beta (B29)FES Feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homologSpermidine/spermine N1-acetyltransferase (SSAT) gene
83Lymphoid-restricted membrane protein (Jaw1) mRNA
( IG TR SM MM GI SV 1S )
Transcriptional activator hSNF2bBLK Protein-tyrosine kinase blkBLK Protein-tyrosine kinase blkBLK Protein-tyrosine kinase blkB94 PROTEINIGHM Immunoglobulin muPPBP Connective tissue activation peptide III
84SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1ANX1 Annexin I (lipocortin I)ADP-ribosyltransferaseADP-ribosyltransferaseADP-ribosyltransferaseHKR-T1ARHG Ras homolog gene family, member G (rho G)GAMMA-INTERFERON-INDUCIBLE PROTEIN IP-30 PRECURSOR
85LEUKOCYTE ELASTASE INHIBITORELA2 Elastatse 2, neutrophilCD19 geneCD19 geneCD19 geneSpermidine/spermine N1-acetyltransferase (SSAT) geneGTF2E2 General transcription factor TFIIE beta subunit, 34 kDGB DEF = Myosin-IE
86MCM3 Minichromosome maintenance deficient (S. cerevisiae) 3
( IG TR SM MM GI SV 1S )
GLRX Glutaredoxin (thioltransferase)HKR-T1HKR-T1HKR-T1HOXA9 Homeo box A9LMP2 genQuiescin (Q6) mRNA, partial cds
87GLRX Glutaredoxin (thioltransferase)LAMP2 Lysosome-associated membrane protein 2 {alternative products}LMP2 genLMP2 genLMP2 genHU-K4 mRNARETINOBLASTOMA BINDING PROTEIN P48PLCB2 Phospholipase C, beta 2
88DCK Deoxycytidine kinase
( IG TR SM MM GI SV 1S )
Pre-B cell enhancing factor (PBEF) mRNAB94 PROTEINB94 PROTEINB94 PROTEINDihydropyrimidinase related protein-2Activin type II receptorB94 PROTEIN
89Max gene extracted from H.sapiens max gene
( IG TR SM MM GI SV 1S )
LMP2 genLYZ LysozymeLYZ LysozymeLYZ LysozymeGRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSORmRNA (clone C-2k) mRNA for serine/threonine protein kinaseCalcyclin
90Dihydrofolate Reductase, Alt. Splice 6
( IG TR SM MM GI SV 1S )
LRPAP1 Low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSORGRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSORGRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSORGTF2E2 General transcription factor TFIIE beta subunit, 34 kDMCM3 Minichromosome maintenance deficient (S. cerevisiae) 3CSPG2 Chondroitin sulfate proteoglycan 2 (versican)
91CD24 signal transducer mRNA and 3' region
( TR SM MM GI SV 1S )
HISTONE H2A.XNPY Neuropeptide YNPY Neuropeptide YNPY Neuropeptide YLMP2 genGB DEF = Erg protein (ets-related gene) mRNAGB DEF = Homeodomain protein HoxA9 mRNA
92GB DEF = Homeodomain protein HoxA9 mRNA
( IG TR SM MM GI SV )
CD24 signal transducer mRNA and 3' regionACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chainRETINOBLASTOMA BINDING PROTEIN P48MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORVIL2 Villin 2 (ezrin)
93MHC-encoded proteasome subunit gene LAMP7-E1 gene (proteasome subunit LMP7) extracted from H.sapiens gene for major histocompatibility complex encoded proteasome subunit LMP7
( IG TR SM MM GI SV 1S )
Quiescin (Q6) mRNA, partial cdsANX1 Annexin I (lipocortin I)ANX1 Annexin I (lipocortin I)ANX1 Annexin I (lipocortin I)Probable GPCR LCR1 HomologTranscriptional activator hSNF2bLMP2 gen
94KIAA0128 gene, partial cds
( IG TR SM MM GI SV 1S )
ADA Adenosine deaminaseELA2 Elastatse 2, neutrophilELA2 Elastatse 2, neutrophilELA2 Elastatse 2, neutrophilDrebrin EINTERLEUKIN-8 PRECURSORmRNA for calcium channel beta3 subunit
95UBIQUITIN-LIKE PROTEIN GDX
( IG TR SM MM GI SV 1S )
(AF1q) mRNAProbable GPCR LCR1 HomologProbable GPCR LCR1 HomologProbable GPCR LCR1 HomologLMNA Lamin AMPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exonEpb72 gene exon 1
96GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE
( IG TR SM MM GI SV 1S )
KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homologPRKCD Protein kinase C, deltaPRKCD Protein kinase C, deltaPRKCD Protein kinase C, deltaInterleukin 8 (IL8) geneTCF3 (E2A immunoglobulin enhancer)TCF3 (E2A immunoglobulin enhancer)
97SP3 Sp3 transcription factor
( IG TR SM MM GI SV 1S )
ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)HU-K4 mRNAHU-K4 mRNAHU-K4 mRNAINTERLEUKIN-8 PRECURSORInterferon-gamma induced protein (IFI 16) genePYGL Glycogen phosphorylase L (liver form)
98Tax1-binding protein TXBP181 mRNA
( IG TR SM MM GI SV 1S )
Acid ceramidase mRNAInterleukin 8 (IL8) geneInterleukin 8 (IL8) geneInterleukin 8 (IL8) geneMEF2A gene (myocyte-specific enhancer factor 2A, C9 form)ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)RABAPTIN-5 protein
99GTF2E2 General transcription factor TFIIE beta subunit, 34 kD
( IG TR GI SV 1S )
CATHEPSIN G PRECURSORINTERLEUKIN-8 PRECURSORINTERLEUKIN-8 PRECURSORINTERLEUKIN-8 PRECURSORZNF91 Zinc finger protein 91 (HPF7, HTF10)Glioma pathogenesis-related protein (GliPR) mRNAEpican, Alt. Splice 11
100DHPS Deoxyhypusine synthase
( IG TR SM MM GI SV 1S )
MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSORPAGA Proliferation-associated gene A (natural killer-enhancing factor A)PAGA Proliferation-associated gene A (natural killer-enhancing factor A)PAGA Proliferation-associated gene A (natural killer-enhancing factor A)LYZ LysozymeMEF2A gene (myocyte-specific enhancer factor 2A, C9 form)LEPR Leptin receptor

Comparison of different measures used by RankGene.

The leftmost column shows the best 100 genes selected by the t-test measure. Every other column corresponds to one of the other measures. In a column for a particular measure, each entry is a colour ranging from white to blue, indicating the difference in the ranks of the gene for that measure and for t-test. The colour is white if the ranks are the same and blue if the difference between the ranks is 100 or more. An interpolated colour between white and blue indicates a difference in rank of less than 100.

Colours used in the table
Rank difference0102030405060708090100
Colour
Gene nameTTIGSVTRGISMMM1S
PROTEASOME IOTA CHAIN
CCND3 Cyclin D3
TCF3 (E2A immunoglobulin enhancer)
MB-1 gene
Zyxin
CD19 gene
Terminal transferase mRNA
MYL1 Myosin light chain (alkali)
Proteoglycan 1
SPTAN1
Immunoglobulin-associated beta (B29)
HKR-T1
GB DEF
hSNF2
RABAPTIN-5 protein
Glutathione S-transferase
CD19 antigen
C-myb
Macmarcks
LPAP gene
Topoisomerase II beta
Oncoprotein 18 (Op18) gene
26-kDa cell surface protein TAPA-1 mRNA
FAH Fumarylacetoacetate
LMP2 gen
ADP-ribosyltransferase
Amyloid beta precursor-like protein
ATP6C Vacuolar H+ ATPase proton channel subunit
CD33 antigen
OBF-1 mRNA for octamer binding factor 1
mRNA for calcium channel beta3 subunit
Transcriptional activator hSNF2b
ALDR1 Aldehyde reductase 1
Inducible protein mRNA
TCF3 (E2A immunoglobulin enhancer)
Nucleoside-diphosphate kinase
Probable GPCR LCR1 Homolog
Yamaguchi sarcoma viral related oncogene homolog
Protective protein for beta-galactosidase
VIL2 Villin 2 (ezrin)
DF D component of complement (adipsin)
T cell leukemia gene
ARHG Ras homolog gene family, member G (rho G)
FTL Ferritin, light polypeptide
IL7R Interleukin 7 receptor
Clone 22 mRNA, alternative splice variant alpha-1
KAI1 Kangai 1
Liver mRNA for interferon-gamma inducing factor
CST3 Cystatin C (amyloid angiopathy and cerebral h
BLK Protein-tyrosine kinase blk
CTSD Cathepsin D (lysosomal aspartyl protease)
ERC-55 mRNA
TIMP2 Tissue inhibitor of metalloproteinase 2
GB DEF = Topoisomerase type II (Topo II) mRNA, par
INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECU
ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 s
KIAA0212 gene
Leukotriene C4 synthase (LTC4S) gene
CRYZ Crystallin zeta (quinone reductase)
KIAA0159 gene
ID3 Inhibitor of DNA binding 3, dominant negative
Translation initiation factor 3 47 kDa subunit mRN
LAMP2 Lysosome-associated membrane protein 2 {alte
RETINOBLASTOMA BINDING PROTEIN P48
Calcineurin A catalytic subunit [human, testis, mR
MCM3 Minichromosome maintenance deficient (S. cere
PAGA Proliferation-associated gene A (natural kill
Thymopoietin (TMPO) gene
IGHM Immunoglobulin mu
GB DEF = Retinoblastoma susceptibility protein (RB
Interferon-gamma induced protein (IFI 16) gene
PCBD 6-pyruvoyl-tetrahydropterin synthase/dimeriza
Thymopoietin beta mRNA
RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin
14-3-3 PROTEIN TAU
KIAA0084 gene, partial cds
RPA1 Replication protein A1 (70kD)
TCF12 Transcription factor 12 (HTF4, helix-loop-he
MSH2 DNA repair protein MSH2
Putative enterocyte differentiation promoting fact
HMG1 High-mobility group (nonhistone chromosomal)
TCRA T cell receptor alpha-chain
Lymphoid-restricted membrane protein (Jaw1) mRNA
SPI1 Spleen focus forming virus (SFFV) proviral in
LEUKOCYTE ELASTASE INHIBITOR
MCM3 Minichromosome maintenance deficient (S. cere
GLRX Glutaredoxin (thioltransferase)
DCK Deoxycytidine kinase
Max gene extracted from H.sapiens max gene
Dihydrofolate Reductase, Alt. Splice 6
CD24 signal transducer mRNA and 3' region
GB DEF = Homeodomain protein HoxA9 mRNA
MHC-encoded proteasome subunit gene LAMP7-E1 gene
KIAA0128 gene, partial cds
UBIQUITIN-LIKE PROTEIN GDX
GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE
SP3 Sp3 transcription factor
Tax1-binding protein TXBP181 mRNA
GTF2E2 General transcription factor TFIIE beta sub
DHPS Deoxyhypusine synthase