Comparison of RankGene Measures for ALL-AML Data of Golub et al.

Comparison of measures in terms of the lists of computed genes.
Comparison of measures in terms of the ranks of computed genes.

**Comparison of different measures used by RankGene**.
Each column shows the best 100 genes selected by the corresponding measure. Using the t-test measure as the gold standard, a gene is highlighted in blue if t-test did not select it among the top 100 genes. A gene selected by the t-test is highlighted in green if it is not selected by at least 2 other measures. The abbreviations for these measures follow the gene name.
	t-test (TT)	Information gain (IG)	Sum of variances (SV)	Twoing rule (TR)	Gini index (GI)	Sum minority (SM)	Max minority (MM)	1D SVM (1S)
1	PROTEASOME IOTA CHAIN	Glutathione S-transferase	CD33 antigen	CD33 antigen	CD33 antigen	CD33 antigen	CD33 antigen	DF D component of complement (adipsin)
2	CCND3 Cyclin D3	CD33 antigen	Zyxin	Zyxin	Zyxin	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	Zyxin
3	TCF3 (E2A immunoglobulin enhancer)	Zyxin	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	Zyxin	Glutathione S-transferase	CD33 antigen
4	MB-1 gene	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	Glutathione S-transferase	Glutathione S-transferase	Glutathione S-transferase	CYSTATIN A	Zyxin	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)
5	Zyxin	Amyloid beta precursor-like protein	TCF3 (E2A immunoglobulin enhancer)	TCF3 (E2A immunoglobulin enhancer)	TCF3 (E2A immunoglobulin enhancer)	DF D component of complement (adipsin)	TCF3 (E2A immunoglobulin enhancer)	TCF3 (E2A immunoglobulin enhancer)
6	CD19 gene ( SM MM )	CYSTATIN A	CYSTATIN A	CYSTATIN A	CYSTATIN A	Glutathione S-transferase	CYSTATIN A	CYSTATIN A
7	Terminal transferase mRNA	DF D component of complement (adipsin)	DF D component of complement (adipsin)	DF D component of complement (adipsin)	DF D component of complement (adipsin)	TCF3 (E2A immunoglobulin enhancer)	DF D component of complement (adipsin)	Glutathione S-transferase
8	MYL1 Myosin light chain (alkali)	TCF3 (E2A immunoglobulin enhancer)	Amyloid beta precursor-like protein	Amyloid beta precursor-like protein	Amyloid beta precursor-like protein	Terminal transferase mRNA	Amyloid beta precursor-like protein	Terminal transferase mRNA
9	Proteoglycan 1	Terminal transferase mRNA	Terminal transferase mRNA	Terminal transferase mRNA	Terminal transferase mRNA	Amyloid beta precursor-like protein	SPTAN1	CCND3 Cyclin D3
10	SPTAN1	PFC Properdin P factor, complement	PFC Properdin P factor, complement	PFC Properdin P factor, complement	PFC Properdin P factor, complement	PFC Properdin P factor, complement	Terminal transferase mRNA	Amyloid beta precursor-like protein
11	Immunoglobulin-associated beta (B29)	CCND3 Cyclin D3	CCND3 Cyclin D3	CCND3 Cyclin D3	CCND3 Cyclin D3	CCND3 Cyclin D3	CCND3 Cyclin D3	CTSD Cathepsin D (lysosomal aspartyl protease)
12	HKR-T1	ARHG Ras homolog gene family, member G (rho G)	GRN Granulin	GRN Granulin	GRN Granulin	GRN Granulin	PFC Properdin P factor, complement	Azurocidin gene
13	GB DEF	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	SPTAN1	Macmarcks	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen
14	hSNF2 ( SM MM )	GRN Granulin	SPTAN1	SPTAN1	SPTAN1	Azurocidin gene	Nuclear Factor Nf-Il6	GRN Granulin
15	RABAPTIN-5 protein ( TR SM MM GI SV )	GB DEF	Azurocidin gene	Azurocidin gene	Azurocidin gene	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	Yamaguchi sarcoma viral related oncogene homolog	MPO Myeloperoxidase
16	Glutathione S-transferase	PROTEASOME IOTA CHAIN	PROTEASOME IOTA CHAIN	PROTEASOME IOTA CHAIN	PROTEASOME IOTA CHAIN	FAH Fumarylacetoacetate	Protective protein for beta-galactosidase	SPTAN1
17	CD19 antigen ( TR SM MM GI SV 1S )	SPTAN1	ARHG Ras homolog gene family, member G (rho G)	ARHG Ras homolog gene family, member G (rho G)	ARHG Ras homolog gene family, member G (rho G)	CTSD Cathepsin D (lysosomal aspartyl protease)	Oncoprotein 18 (Op18) gene	Proteoglycan 1
18	C-myb	MB-1 gene	MYL1 Myosin light chain (alkali)	MYL1 Myosin light chain (alkali)	MYL1 Myosin light chain (alkali)	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	FAH Fumarylacetoacetate	Yamaguchi sarcoma viral related oncogene homolog
19	Macmarcks	Azurocidin gene	CTSD Cathepsin D (lysosomal aspartyl protease)	CTSD Cathepsin D (lysosomal aspartyl protease)	CTSD Cathepsin D (lysosomal aspartyl protease)	PROTEASOME IOTA CHAIN	CTSD Cathepsin D (lysosomal aspartyl protease)	PFC Properdin P factor, complement
20	LPAP gene	Immunoglobulin-associated beta (B29)	FAH Fumarylacetoacetate	FAH Fumarylacetoacetate	FAH Fumarylacetoacetate	MYL1 Myosin light chain (alkali)	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	Protective protein for beta-galactosidase
21	Topoisomerase II beta	MYL1 Myosin light chain (alkali)	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	Macmarcks	Azurocidin gene	MB-1 gene
22	Oncoprotein 18 (Op18) gene	Proteoglycan 1	GB DEF	GB DEF	GB DEF	Nuclear Factor Nf-Il6	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	FAH Fumarylacetoacetate
23	26-kDa cell surface protein TAPA-1 mRNA ( IG TR SM MM GI SV )	Recombination activating protein (RAG-1) gene	Proteoglycan 1	Proteoglycan 1	Proteoglycan 1	Yamaguchi sarcoma viral related oncogene homolog	GRN Granulin	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)
24	FAH Fumarylacetoacetate	MPO Myeloperoxidase	MPO Myeloperoxidase	MPO Myeloperoxidase	MPO Myeloperoxidase	MPO Myeloperoxidase	ME491 gene extracted from H.sapiens gene for Me491/CD63 antigen	MYL1 Myosin light chain (alkali)
25	LMP2 gen	Leukotriene C4 synthase (LTC4S) gene	Leukotriene C4 synthase (LTC4S) gene	Leukotriene C4 synthase (LTC4S) gene	Leukotriene C4 synthase (LTC4S) gene	Protective protein for beta-galactosidase	Uridine phosphorylase	Leukotriene C4 synthase (LTC4S) gene
26	ADP-ribosyltransferase ( SM MM 1S )	CTSD Cathepsin D (lysosomal aspartyl protease)	MB-1 gene	MB-1 gene	MB-1 gene	Oncoprotein 18 (Op18) gene	C-myb	PROTEASOME IOTA CHAIN
27	Amyloid beta precursor-like protein	FAH Fumarylacetoacetate	Yamaguchi sarcoma viral related oncogene homolog	Yamaguchi sarcoma viral related oncogene homolog	Yamaguchi sarcoma viral related oncogene homolog	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	TIMP2 Tissue inhibitor of metalloproteinase 2	Macmarcks
28	ATP6C Vacuolar H+ ATPase proton channel subunit	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	Leukotriene C4 synthase (LTC4S) gene	MYL1 Myosin light chain (alkali)	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)
29	CD33 antigen	CLU Clusterin (complement lysis inhibitor; testosterone-repressed prostate message 2; apolipoprotein J)	Macmarcks	Macmarcks	Macmarcks	Proteoglycan 1	KIAA0022 gene	Topoisomerase II beta
30	OBF-1 mRNA for octamer binding factor 1	T cell leukemia gene	Protective protein for beta-galactosidase	Protective protein for beta-galactosidase	Protective protein for beta-galactosidase	ARHG Ras homolog gene family, member G (rho G)	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	ARHG Ras homolog gene family, member G (rho G)
31	mRNA for calcium channel beta3 subunit ( IG TR SM MM GI SV )	TCRA T cell receptor alpha-chain	Oncoprotein 18 (Op18) gene	Oncoprotein 18 (Op18) gene	Oncoprotein 18 (Op18) gene	Topoisomerase II beta	MPO Myeloperoxidase	INTERLEUKIN-8 PRECURSOR
32	Transcriptional activator hSNF2b ( TR SM GI SV 1S )	Yamaguchi sarcoma viral related oncogene homolog	NF-IL6-beta protein mRNA	NF-IL6-beta protein mRNA	NF-IL6-beta protein mRNA	NF-IL6-beta protein mRNA	LEUKOCYTE ELASTASE INHIBITOR	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1
33	ALDR1 Aldehyde reductase 1 ( IG TR SM GI SV )	OBF-1 mRNA for octamer binding factor 1	Nuclear Factor Nf-Il6	Nuclear Factor Nf-Il6	Nuclear Factor Nf-Il6	KIAA0022 gene	Pre-B cell enhancing factor (PBEF) mRNA	ATP6C Vacuolar H+ ATPase proton channel subunit
34	Inducible protein mRNA	Topoisomerase II beta	Topoisomerase II beta	Topoisomerase II beta	Topoisomerase II beta	GB DEF	MB-1 gene	GB DEF
35	TCF3 (E2A immunoglobulin enhancer) ( IG TR SM GI SV )	KIAA0159 gene	KIAA0022 gene	KIAA0022 gene	KIAA0022 gene	FTL Ferritin, light polypeptide	Proteoglycan 1	Lysozyme gene (EC 3.2.1.17)
36	Nucleoside-diphosphate kinase	BLK Protein-tyrosine kinase blk	Immunoglobulin-associated beta (B29)	Immunoglobulin-associated beta (B29)	Immunoglobulin-associated beta (B29)	PYGL Glycogen phosphorylase L (liver form)	PROTEASOME IOTA CHAIN	FTL Ferritin, light polypeptide
37	Probable GPCR LCR1 Homolog ( IG 1S )	Protective protein for beta-galactosidase	LEUKOCYTE ELASTASE INHIBITOR	LEUKOCYTE ELASTASE INHIBITOR	LEUKOCYTE ELASTASE INHIBITOR	Fc-epsilon-receptor gamma-chain mRNA	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	Inducible protein mRNA
38	Yamaguchi sarcoma viral related oncogene homolog	Macmarcks	Uridine phosphorylase	Uridine phosphorylase	Uridine phosphorylase	ATP6C Vacuolar H+ ATPase proton channel subunit	GLRX Glutaredoxin (thioltransferase)	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7
39	Protective protein for beta-galactosidase	Oncoprotein 18 (Op18) gene	Epb72 gene exon 1	Epb72 gene exon 1	Epb72 gene exon 1	LEUKOCYTE ELASTASE INHIBITOR	GB DEF = Myosin-IE	SELL Leukocyte adhesion protein beta subunit
40	VIL2 Villin 2 (ezrin) ( IG TR SM GI SV )	KIAA0022 gene	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	BB1	Nucleoside-diphosphate kinase	PLECKSTRIN
41	DF D component of complement (adipsin)	Inducible protein mRNA	Inducible protein mRNA	Inducible protein mRNA	Inducible protein mRNA	MB-1 gene	OBF-1 mRNA for octamer binding factor 1	Interleukin 8 (IL8) gene
42	T cell leukemia gene ( SM MM 1S )	PLECKSTRIN	PLECKSTRIN	PLECKSTRIN	PLECKSTRIN	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta
43	ARHG Ras homolog gene family, member G (rho G)	NF-IL6-beta protein mRNA	C-myb	C-myb	C-myb	Uridine phosphorylase	Topoisomerase II beta	TIMP2 Tissue inhibitor of metalloproteinase 2
44	FTL Ferritin, light polypeptide	Nuclear Factor Nf-Il6	TIMP2 Tissue inhibitor of metalloproteinase 2	TIMP2 Tissue inhibitor of metalloproteinase 2	TIMP2 Tissue inhibitor of metalloproteinase 2	C-myb	Probable GPCR LCR1 Homolog	Fc-epsilon-receptor gamma-chain mRNA
45	IL7R Interleukin 7 receptor	IL7R Interleukin 7 receptor	FTL Ferritin, light polypeptide	FTL Ferritin, light polypeptide	FTL Ferritin, light polypeptide	MANB Mannosidase alpha-B (lysosomal)	SELL Leukocyte adhesion protein beta subunit	LYZ Lysozyme
46	Clone 22 mRNA, alternative splice variant alpha-1 ( IG TR SM MM GI SV 1S )	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	PYGL Glycogen phosphorylase L (liver form)	PYGL Glycogen phosphorylase L (liver form)	PYGL Glycogen phosphorylase L (liver form)	TIMP2 Tissue inhibitor of metalloproteinase 2	NF-IL6-beta protein mRNA	hSNF2
47	KAI1 Kangai 1 ( IG TR SM MM GI SV 1S )	CD19 gene	ATP6C Vacuolar H+ ATPase proton channel subunit	ATP6C Vacuolar H+ ATPase proton channel subunit	ATP6C Vacuolar H+ ATPase proton channel subunit	SELL Leukocyte adhesion protein beta subunit	Epb72 gene exon 1	C-myb
48	Liver mRNA for interferon-gamma inducing factor ( IG TR GI SV )	LEUKOCYTE ELASTASE INHIBITOR	MANB Mannosidase alpha-B (lysosomal)	MANB Mannosidase alpha-B (lysosomal)	MANB Mannosidase alpha-B (lysosomal)	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	LYZ Lysozyme
49	CST3 Cystatin C (amyloid angiopathy and cerebral hemorrhage)	Uridine phosphorylase	SELL Leukocyte adhesion protein beta subunit	SELL Leukocyte adhesion protein beta subunit	SELL Leukocyte adhesion protein beta subunit	Interferon-gamma induced protein (IFI 16) gene	Liver mRNA for interferon-gamma inducing factor	Nuclear Factor Nf-Il6
50	BLK Protein-tyrosine kinase blk ( SM MM 1S )	Epb72 gene exon 1	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	Epb72 gene exon 1	Calcyclin	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
51	CTSD Cathepsin D (lysosomal aspartyl protease)	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	Lysozyme gene (EC 3.2.1.17)	Lysozyme gene (EC 3.2.1.17)	Lysozyme gene (EC 3.2.1.17)	Lysozyme gene (EC 3.2.1.17)	TALDO Transaldolase	NF-IL6-beta protein mRNA
52	ERC-55 mRNA ( IG TR SM MM GI SV 1S )	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR	OBF-1 mRNA for octamer binding factor 1	OBF-1 mRNA for octamer binding factor 1	OBF-1 mRNA for octamer binding factor 1	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	ALCAM Activated leucocyte cell adhesion molecule	Uridine phosphorylase
53	TIMP2 Tissue inhibitor of metalloproteinase 2	FTL Ferritin, light polypeptide	Recombination activating protein (RAG-1) gene	Recombination activating protein (RAG-1) gene	Recombination activating protein (RAG-1) gene	CATHEPSIN G PRECURSOR	PCBD 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)	LMNA Lamin A
54	GB DEF = Topoisomerase type II (Topo II) mRNA, partial cds ( IG TR SM MM GI SV 1S )	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	Inducible protein mRNA	CD19 gene
55	INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECURSOR ( TR SM MM GI SV 1S )	PYGL Glycogen phosphorylase L (liver form)	Interferon-gamma induced protein (IFI 16) gene	Interferon-gamma induced protein (IFI 16) gene	Interferon-gamma induced protein (IFI 16) gene	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR	FTL Ferritin, light polypeptide	LPAP gene
56	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain ( SM 1S )	ATP6C Vacuolar H+ ATPase proton channel subunit	Fc-epsilon-receptor gamma-chain mRNA	Fc-epsilon-receptor gamma-chain mRNA	Fc-epsilon-receptor gamma-chain mRNA	Quiescin (Q6) mRNA, partial cds	ADA Adenosine deaminase	Liver mRNA for interferon-gamma inducing factor
57	KIAA0212 gene ( IG TR SM MM GI SV 1S )	MANB Mannosidase alpha-B (lysosomal)	BB1	BB1	BB1	Inducible protein mRNA	PYGL Glycogen phosphorylase L (liver form)	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR
58	Leukotriene C4 synthase (LTC4S) gene	SELL Leukocyte adhesion protein beta subunit	GB DEF = Myosin-IE	GB DEF = Myosin-IE	GB DEF = Myosin-IE	ADA Adenosine deaminase	Recombination activating protein (RAG-1) gene	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon
59	CRYZ Crystallin zeta (quinone reductase) ( IG TR SM MM GI SV 1S )	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR	PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR	IL7R Interleukin 7 receptor	IL7R Interleukin 7 receptor	Oncoprotein 18 (Op18) gene
60	KIAA0159 gene ( SM MM 1S )	Lysozyme gene (EC 3.2.1.17)	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	PTX3 Pentaxin-related gene, rapidly induced by IL-1 beta	L-kynurenine hydrolase mRNA
61	ID3 Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein ( IG TR SM MM GI SV 1S )	C-myb	T cell leukemia gene	T cell leukemia gene	T cell leukemia gene	Pre-B cell enhancing factor (PBEF) mRNA	Fc-epsilon-receptor gamma-chain mRNA	Pre-B cell enhancing factor (PBEF) mRNA
62	Translation initiation factor 3 47 kDa subunit mRNA ( IG TR SM MM GI SV 1S )	TIMP2 Tissue inhibitor of metalloproteinase 2	TCRA T cell receptor alpha-chain	TCRA T cell receptor alpha-chain	TCRA T cell receptor alpha-chain	(AF1q) mRNA	PPBP Connective tissue activation peptide III	LEUKOCYTE ELASTASE INHIBITOR
63	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	ADP-ribosyltransferase	Nucleoside-diphosphate kinase	Nucleoside-diphosphate kinase	Nucleoside-diphosphate kinase	Acid ceramidase mRNA	ATP6C Vacuolar H+ ATPase proton channel subunit	OBF-1 mRNA for octamer binding factor 1
64	RETINOBLASTOMA BINDING PROTEIN P48 ( IG TR GI SV 1S )	hSNF2	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	PLECKSTRIN	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	HKR-T1
65	Calcineurin A catalytic subunit [human, testis, mRNA, 2134 nt] ( IG TR SM MM GI SV 1S )	CHRNA7 Cholinergic receptor, nicotinic, alpha polypeptide 7	Nek3 mRNA for protein kinase	LPAP gene	Nek3 mRNA for protein kinase	GLRX Glutaredoxin (thioltransferase)	SPTBN1 Spectrin, beta, non-erythrocytic 1	LRPAP1 Low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1
66	MCM3 Minichromosome maintenance deficient (S. cerevisiae) 3 ( IG TR SM GI SV 1S )	Interferon-gamma induced protein (IFI 16) gene	LPAP gene	Nek3 mRNA for protein kinase	LPAP gene	GB DEF = Myosin-IE	HKR-T1	PRKCD Protein kinase C, delta
67	PAGA Proliferation-associated gene A (natural killer-enhancing factor A) ( SM MM 1S )	Fc-epsilon-receptor gamma-chain mRNA	Calcyclin	Calcyclin	Calcyclin	Nucleoside-diphosphate kinase	BB1	IL7R Interleukin 7 receptor
68	Thymopoietin (TMPO) gene ( IG TR SM MM GI SV 1S )	BB1	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	Nek3 mRNA for protein kinase	(AF1q) mRNA	KIAA0022 gene
69	IGHM Immunoglobulin mu ( IG TR SM GI SV 1S )	GB DEF = Myosin-IE	Pre-B cell enhancing factor (PBEF) mRNA	Pre-B cell enhancing factor (PBEF) mRNA	Pre-B cell enhancing factor (PBEF) mRNA	OBF-1 mRNA for octamer binding factor 1	Spermidine/spermine N1-acetyltransferase (SSAT) gene	26-kDa cell surface protein TAPA-1 mRNA
70	GB DEF = Retinoblastoma susceptibility protein (RB1) gene, with a 3 bp deletion in exon 22 (L11910 bases 161855-162161) ( IG TR SM MM GI SV 1S )	NPY Neuropeptide Y	GLRX Glutaredoxin (thioltransferase)	GLRX Glutaredoxin (thioltransferase)	GLRX Glutaredoxin (thioltransferase)	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	HOXA9 Homeo box A9	CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)
71	Interferon-gamma induced protein (IFI 16) gene	RABAPTIN-5 protein	Quiescin (Q6) mRNA, partial cds	Quiescin (Q6) mRNA, partial cds	Quiescin (Q6) mRNA, partial cds	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	Leukotriene C4 synthase (LTC4S) gene	LAMP2 Lysosome-associated membrane protein 2 {alternative products}
72	PCBD 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) ( IG TR SM GI SV 1S )	CD19 antigen	ADA Adenosine deaminase	ADA Adenosine deaminase	ADA Adenosine deaminase	KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	Small GTP-binding protein mRNA	Acid ceramidase mRNA
73	Thymopoietin beta mRNA ( IG TR SM MM GI SV 1S )	Calcyclin	(AF1q) mRNA	(AF1q) mRNA	(AF1q) mRNA	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	L-kynurenine hydrolase mRNA	ALDR1 Aldehyde reductase 1
74	RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin; EDN)	PAGA Proliferation-associated gene A (natural killer-enhancing factor A)	KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)	Acid ceramidase mRNA	GRO2 GRO2 oncogene
75	14-3-3 PROTEIN TAU ( IG TR SM MM GI SV 1S )	LPAP gene	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	LPAP gene	LOT1 mRNA	LYZ Lysozyme
76	KIAA0084 gene, partial cds ( IG TR SM MM GI SV 1S )	B94 PROTEIN	Acid ceramidase mRNA	Acid ceramidase mRNA	Acid ceramidase mRNA	Hunc18b2	DNA binding protein homolog (DRIL) mRNA, partial cds	BB1
77	RPA1 Replication protein A1 (70kD) ( IG TR SM MM GI SV 1S )	LYZ Lysozyme	CATHEPSIN G PRECURSOR	CATHEPSIN G PRECURSOR	CATHEPSIN G PRECURSOR	PRKCD Protein kinase C, delta	Dihydropyrimidinase related protein-2	PI Protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin
78	TCF12 Transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) ( IG TR SM MM GI SV 1S )	Nucleoside-diphosphate kinase	IL7R Interleukin 7 receptor	IL7R Interleukin 7 receptor	IL7R Interleukin 7 receptor	Liver mRNA for interferon-gamma inducing factor	PLECKSTRIN	MANB Mannosidase alpha-B (lysosomal)
79	MSH2 DNA repair protein MSH2 ( IG TR SM MM GI SV 1S )	P4HB Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide (protein disulfide isomerase; thyroid hormone binding protein p55)	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	Calcyclin	ALDR1 Aldehyde reductase 1	Phosphotyrosine independent ligand p62 for the Lck SH2 domain mRNA
80	Putative enterocyte differentiation promoting factor mRNA, partial cds ( IG TR SM MM GI SV 1S )	Nek3 mRNA for protein kinase	CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)	CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)	CD36 CD36 antigen (collagen type I receptor, thrombospondin receptor)	Recombination activating protein (RAG-1) gene	GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR	(AF1q) mRNA
81	HMG1 High-mobility group (nonhistone chromosomal) protein 1 ( IG TR SM MM GI SV 1S )	INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECURSOR	hSNF2	hSNF2	hSNF2	PPBP Connective tissue activation peptide III	VIL2 Villin 2 (ezrin)	Immunoglobulin-associated beta (B29)
82	TCRA T cell receptor alpha-chain ( SM MM 1S )	HKR-T1	KIAA0159 gene	KIAA0159 gene	KIAA0159 gene	Immunoglobulin-associated beta (B29)	FES Feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog	Spermidine/spermine N1-acetyltransferase (SSAT) gene
83	Lymphoid-restricted membrane protein (Jaw1) mRNA ( IG TR SM MM GI SV 1S )	Transcriptional activator hSNF2b	BLK Protein-tyrosine kinase blk	BLK Protein-tyrosine kinase blk	BLK Protein-tyrosine kinase blk	B94 PROTEIN	IGHM Immunoglobulin mu	PPBP Connective tissue activation peptide III
84	SPI1 Spleen focus forming virus (SFFV) proviral integration oncogene spi1	ANX1 Annexin I (lipocortin I)	ADP-ribosyltransferase	ADP-ribosyltransferase	ADP-ribosyltransferase	HKR-T1	ARHG Ras homolog gene family, member G (rho G)	GAMMA-INTERFERON-INDUCIBLE PROTEIN IP-30 PRECURSOR
85	LEUKOCYTE ELASTASE INHIBITOR	ELA2 Elastatse 2, neutrophil	CD19 gene	CD19 gene	CD19 gene	Spermidine/spermine N1-acetyltransferase (SSAT) gene	GTF2E2 General transcription factor TFIIE beta subunit, 34 kD	GB DEF = Myosin-IE
86	MCM3 Minichromosome maintenance deficient (S. cerevisiae) 3 ( IG TR SM MM GI SV 1S )	GLRX Glutaredoxin (thioltransferase)	HKR-T1	HKR-T1	HKR-T1	HOXA9 Homeo box A9	LMP2 gen	Quiescin (Q6) mRNA, partial cds
87	GLRX Glutaredoxin (thioltransferase)	LAMP2 Lysosome-associated membrane protein 2 {alternative products}	LMP2 gen	LMP2 gen	LMP2 gen	HU-K4 mRNA	RETINOBLASTOMA BINDING PROTEIN P48	PLCB2 Phospholipase C, beta 2
88	DCK Deoxycytidine kinase ( IG TR SM MM GI SV 1S )	Pre-B cell enhancing factor (PBEF) mRNA	B94 PROTEIN	B94 PROTEIN	B94 PROTEIN	Dihydropyrimidinase related protein-2	Activin type II receptor	B94 PROTEIN
89	Max gene extracted from H.sapiens max gene ( IG TR SM MM GI SV 1S )	LMP2 gen	LYZ Lysozyme	LYZ Lysozyme	LYZ Lysozyme	GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR	mRNA (clone C-2k) mRNA for serine/threonine protein kinase	Calcyclin
90	Dihydrofolate Reductase, Alt. Splice 6 ( IG TR SM MM GI SV 1S )	LRPAP1 Low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1	GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR	GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR	GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR RECEPTOR ALPHA CHAIN PRECURSOR	GTF2E2 General transcription factor TFIIE beta subunit, 34 kD	MCM3 Minichromosome maintenance deficient (S. cerevisiae) 3	CSPG2 Chondroitin sulfate proteoglycan 2 (versican)
91	CD24 signal transducer mRNA and 3' region ( TR SM MM GI SV 1S )	HISTONE H2A.X	NPY Neuropeptide Y	NPY Neuropeptide Y	NPY Neuropeptide Y	LMP2 gen	GB DEF = Erg protein (ets-related gene) mRNA	GB DEF = Homeodomain protein HoxA9 mRNA
92	GB DEF = Homeodomain protein HoxA9 mRNA ( IG TR SM MM GI SV )	CD24 signal transducer mRNA and 3' region	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain	RETINOBLASTOMA BINDING PROTEIN P48	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	VIL2 Villin 2 (ezrin)
93	MHC-encoded proteasome subunit gene LAMP7-E1 gene (proteasome subunit LMP7) extracted from H.sapiens gene for major histocompatibility complex encoded proteasome subunit LMP7 ( IG TR SM MM GI SV 1S )	Quiescin (Q6) mRNA, partial cds	ANX1 Annexin I (lipocortin I)	ANX1 Annexin I (lipocortin I)	ANX1 Annexin I (lipocortin I)	Probable GPCR LCR1 Homolog	Transcriptional activator hSNF2b	LMP2 gen
94	KIAA0128 gene, partial cds ( IG TR SM MM GI SV 1S )	ADA Adenosine deaminase	ELA2 Elastatse 2, neutrophil	ELA2 Elastatse 2, neutrophil	ELA2 Elastatse 2, neutrophil	Drebrin E	INTERLEUKIN-8 PRECURSOR	mRNA for calcium channel beta3 subunit
95	UBIQUITIN-LIKE PROTEIN GDX ( IG TR SM MM GI SV 1S )	(AF1q) mRNA	Probable GPCR LCR1 Homolog	Probable GPCR LCR1 Homolog	Probable GPCR LCR1 Homolog	LMNA Lamin A	MPO from Human myeloperoxidase gene, exons 1-4./ntype=DNA /annot=exon	Epb72 gene exon 1
96	GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE ( IG TR SM MM GI SV 1S )	KIT V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	PRKCD Protein kinase C, delta	PRKCD Protein kinase C, delta	PRKCD Protein kinase C, delta	Interleukin 8 (IL8) gene	TCF3 (E2A immunoglobulin enhancer)	TCF3 (E2A immunoglobulin enhancer)
97	SP3 Sp3 transcription factor ( IG TR SM MM GI SV 1S )	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	HU-K4 mRNA	HU-K4 mRNA	HU-K4 mRNA	INTERLEUKIN-8 PRECURSOR	Interferon-gamma induced protein (IFI 16) gene	PYGL Glycogen phosphorylase L (liver form)
98	Tax1-binding protein TXBP181 mRNA ( IG TR SM MM GI SV 1S )	Acid ceramidase mRNA	Interleukin 8 (IL8) gene	Interleukin 8 (IL8) gene	Interleukin 8 (IL8) gene	MEF2A gene (myocyte-specific enhancer factor 2A, C9 form)	ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide)	RABAPTIN-5 protein
99	GTF2E2 General transcription factor TFIIE beta subunit, 34 kD ( IG TR GI SV 1S )	CATHEPSIN G PRECURSOR	INTERLEUKIN-8 PRECURSOR	INTERLEUKIN-8 PRECURSOR	INTERLEUKIN-8 PRECURSOR	ZNF91 Zinc finger protein 91 (HPF7, HTF10)	Glioma pathogenesis-related protein (GliPR) mRNA	Epican, Alt. Splice 11
100	DHPS Deoxyhypusine synthase ( IG TR SM MM GI SV 1S )	MACROPHAGE INFLAMMATORY PROTEIN 1-ALPHA PRECURSOR	PAGA Proliferation-associated gene A (natural killer-enhancing factor A)	PAGA Proliferation-associated gene A (natural killer-enhancing factor A)	PAGA Proliferation-associated gene A (natural killer-enhancing factor A)	LYZ Lysozyme	MEF2A gene (myocyte-specific enhancer factor 2A, C9 form)	LEPR Leptin receptor

Comparison of different measures used by RankGene.

The leftmost column shows the best 100 genes selected by the t-test measure. Every other column corresponds to one of the other measures. In a column for a particular measure, each entry is a colour ranging from white to blue, indicating the difference in the ranks of the gene for that measure and for t-test. The colour is white if the ranks are the same and blue if the difference between the ranks is 100 or more. An interpolated colour between white and blue indicates a difference in rank of less than 100.

**Colours used in the table**
Rank difference	0	10	20	30	40	50	60	70	80	90	100
Colour

Gene name

PROTEASOME IOTA CHAIN

CCND3 Cyclin D3

TCF3 (E2A immunoglobulin enhancer)

MB-1 gene

Zyxin

CD19 gene

Terminal transferase mRNA

MYL1 Myosin light chain (alkali)

Proteoglycan 1

SPTAN1

Immunoglobulin-associated beta (B29)

HKR-T1

GB DEF

hSNF2

RABAPTIN-5 protein

Glutathione S-transferase

CD19 antigen

C-myb

Macmarcks

LPAP gene

Topoisomerase II beta

Oncoprotein 18 (Op18) gene

26-kDa cell surface protein TAPA-1 mRNA

FAH Fumarylacetoacetate

LMP2 gen

ADP-ribosyltransferase

Amyloid beta precursor-like protein

ATP6C Vacuolar H+ ATPase proton channel subunit

CD33 antigen

OBF-1 mRNA for octamer binding factor 1

mRNA for calcium channel beta3 subunit

Transcriptional activator hSNF2b

ALDR1 Aldehyde reductase 1

Inducible protein mRNA

TCF3 (E2A immunoglobulin enhancer)

Nucleoside-diphosphate kinase

Probable GPCR LCR1 Homolog

Yamaguchi sarcoma viral related oncogene homolog

Protective protein for beta-galactosidase

VIL2 Villin 2 (ezrin)

DF D component of complement (adipsin)

T cell leukemia gene

ARHG Ras homolog gene family, member G (rho G)

FTL Ferritin, light polypeptide

IL7R Interleukin 7 receptor

Clone 22 mRNA, alternative splice variant alpha-1

KAI1 Kangai 1

Liver mRNA for interferon-gamma inducing factor

CST3 Cystatin C (amyloid angiopathy and cerebral h

BLK Protein-tyrosine kinase blk

CTSD Cathepsin D (lysosomal aspartyl protease)

ERC-55 mRNA

TIMP2 Tissue inhibitor of metalloproteinase 2

GB DEF = Topoisomerase type II (Topo II) mRNA, par

INTERFERON GAMMA UP-REGULATED I-5111 PROTEIN PRECU

ACADM Acyl-Coenzyme A dehydrogenase, C-4 to C-12 s

KIAA0212 gene

Leukotriene C4 synthase (LTC4S) gene

CRYZ Crystallin zeta (quinone reductase)

KIAA0159 gene

ID3 Inhibitor of DNA binding 3, dominant negative

Translation initiation factor 3 47 kDa subunit mRN

LAMP2 Lysosome-associated membrane protein 2 {alte

RETINOBLASTOMA BINDING PROTEIN P48

Calcineurin A catalytic subunit [human, testis, mR

MCM3 Minichromosome maintenance deficient (S. cere

PAGA Proliferation-associated gene A (natural kill

Thymopoietin (TMPO) gene

IGHM Immunoglobulin mu

GB DEF = Retinoblastoma susceptibility protein (RB

Interferon-gamma induced protein (IFI 16) gene

PCBD 6-pyruvoyl-tetrahydropterin synthase/dimeriza

Thymopoietin beta mRNA

RNS2 Ribonuclease 2 (eosinophil-derived neurotoxin

14-3-3 PROTEIN TAU

KIAA0084 gene, partial cds

RPA1 Replication protein A1 (70kD)

TCF12 Transcription factor 12 (HTF4, helix-loop-he

MSH2 DNA repair protein MSH2

Putative enterocyte differentiation promoting fact

HMG1 High-mobility group (nonhistone chromosomal)

TCRA T cell receptor alpha-chain

Lymphoid-restricted membrane protein (Jaw1) mRNA

SPI1 Spleen focus forming virus (SFFV) proviral in

LEUKOCYTE ELASTASE INHIBITOR

MCM3 Minichromosome maintenance deficient (S. cere

GLRX Glutaredoxin (thioltransferase)

DCK Deoxycytidine kinase

Max gene extracted from H.sapiens max gene

Dihydrofolate Reductase, Alt. Splice 6

CD24 signal transducer mRNA and 3' region

GB DEF = Homeodomain protein HoxA9 mRNA

MHC-encoded proteasome subunit gene LAMP7-E1 gene

KIAA0128 gene, partial cds

UBIQUITIN-LIKE PROTEIN GDX

GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE

SP3 Sp3 transcription factor

Tax1-binding protein TXBP181 mRNA

GTF2E2 General transcription factor TFIIE beta sub

DHPS Deoxyhypusine synthase